Shoppers and team members at Coles Port Pirie raised more than $26,000 through the sale of beanies in a six-week campaign to help find a cure for Motor Neurone Disease.
The store was among the top five fundraisers in the state, placing second behind Coles St Agnes.
Across the country, Coles raised more than $5 million for FightMND and South Australian stores together raised over $480,000.
Coles Port Pirie store manager Rob Fairman said he was amazed by the outpour of support from the community.
"I wouldn't say it is the easiest time right now to donate, but I am really proud of the community and our team who have helped make a difference in that research," Mr Fairman said.
Mr Fairman said it was the first year the store had sold beanies and he couldn't have asked for a better response.
"As soon as the beanies came in we set them up at the front of the store and our first allocation of 400 sold out within two days," he said.
The store also held an in-store raffle in which they received some donations from local businesses and raised close to $500 for FightMND.
Mr Fairman said he is proud of the community's effort to pull together and support the fight for Motor Neurone Disease.
"The team members loved it ... there are a few team members in the store who are more close to the disease and they were some of the main drivers of the raffle," he said.
FightMND CEO Jamie Howden said Coles' willingness to broaden its support through their extensive network of supermarkets nationwide contributed significantly to the campaign.
"Having Coles on board to sell beanies this year has made a huge impact in the fight against Motor Neurone Disease and on this campaign specifically which faced many challenges due to the restrictions of COVID-19," Mr Howden said.
"Not only does this partnership raise vital funds for Motor Neurone Disease medical research, it also provides an amazing national platform for FightMND to mobilise the message and awareness of how devastating the disease is.
"We are extremely grateful to Coles and Aussie pork farmers for their ongoing support of FightMND."